Depends on your personal likes too.
A lot of people like Triple Threads (a relatively high end product) but me personally I don't really care for the looks of it so I don't see myself buying boxes of it. I'll trade for a few cards of my PC guys from it of course.
Also depends on your definition of rookie hits. Bowman, Bowman Chrome, Bowman Draft all have potential, i.e. a lot of minor league prospects that may or may not pan out and may take a few years to do so. We don't get a lot of Stephen Strasburg / Bryce Harper / Mike Trouts that jump in that quickly and do that well - those guys are once a decade really.
Topps is your standard issue - would have called the core set "lower end" in the past but it appears some others have come out recently to take that part of the market so the core set now falls in the mid range IMHO. Topps Chrome, Topps Finest, Topps Tier One are all higher end products. One thing Topps core set typically has is a couple of autos / mem cards per box whereas a lot of the other products only have 1 auto / mem card per box.
Are you looking to prospect / potentially make money off quick turnarounds of cards? Or you looking to find a few players and teams you are gonna collect more of while enjoying the addiction of busting boxes and not really in it for the money per se? Me personally I'm a collector and don't really sell much of my stuff.
You might check out Sports Card Radio's list of reviews/previews to see samples of the various sets. They do a great job of indicating how many autos/mem cards per box, give some sample images, list out the variations and inserts, etc.
http://sportscardradio.com/index.php/pro...-a-reviews
And I apologize now for saying a lot but not necessarily answering your question lol